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Chemical probes against cancer

Craven Lab | Gregory Craven | Yale University

Welcome to the Craven Lab

We design small molecule inhibitors and chemical tools to probe and perturb dysregulated signaling pathways, especially in cancer. 

Our interdisciplinary research combines:

  • Small-molecule design and synthesis
  • Proteomic mass spectrometry
  • Structural biology and biochemistry

We like to exploit covalent inhibition, stereochemistry, and metal-binding to uncover new biology and inform therapeutic strategies in cancer.