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Chemical probes against cancer

Craven Lab | Gregory Craven | Yale University

Welcome to the Craven Lab

Led by Gregory Craven, we design small molecule inhibitors and chemical tools to probe and perturb dysregulated signaling pathways, especially in cancer. 

Our interdisciplinary research combines:

  • Small-molecule design and synthesis
  • Proteomic mass spectrometry
  • Structural biology and biochemistry

We like to exploit covalent inhibition, stereochemistry, and metal-binding to uncover new biology and inform therapeutic strategies in cancer.